Effect of recurrent task-induced acute stress on task performance, vagally mediated heart rate variability, and task-evoked pupil response.

Advances in wearable sensor technologies can be leveraged to investigate behavioral and physiological responses in task-induced stress environments. Reliable and valid multidimensional assessments are required to detect stress given its multidimensional nature. This study investigated the effect of recurrent task-induced acute stress on task performance, vagally mediated heart variability measures (vmHRV) and task-evoked pupillary response (TEPR). Task performance, vmHRV measures, and TEPR were collected from 32 study participants while they performed a computer-based task in a recurrent task-induced acute stress environment. Mixed-effects modeling was used to assess the sensitivity of each outcome variable to experimental conditions. Repeated measures correlation tests were used to examine associations between outcome variables. Task performance degraded under stress. vmHRV measures were lower in the stress conditions relative to the no stress conditions. TEPR was found to be higher in the stress conditions compared to the no stress conditions. Task performance was negatively associated with the vmHRV measures, and degraded task performance was linked to increased TEPR in the stress conditions. There were positive associations between vmHRV measures. TEPR was negatively associated with vmHRV measures. Although task-induced stress degrades task performance, recurrent exposure to that stress could alter this effect via habituation. Further, our findings suggest that vmHRV measures and TEPR are sensitive enough to quantify psychophysiological responses to recurrent task-induced stress.

State of the evidence on simulation-based electronic health records training: A scoping review.

This study synthesized the available evidence of simulation-based electronic health records (EHRs) training in educational and clinical environments for healthcare providers in the literature. The Arksey and O'Malley methodological framework was employed. A systematic search was carried out in relevant databases from inception to January 2020, identifying 24 studies for inclusion. Three themes emerged: (a) role of simulation-based EHR training in evaluating improvement interventions, (b) debriefing and feedback methods used, and (c) challenges of evaluating simulation-based EHR training. The majority of the studies aimed to emphasize the practical skills of individual medical trainees and employed post-simulation feedback as the feedback method. Future research should focus on (a) using simulation-based EHR training to achieve specific learning goals, (b) investigating aspects of clinical performance that are susceptible to skill decay, and (c) examining the influence of simulation-based EHR training on team dynamics.

Assessment of Radiation Therapy Technologists' Workload and Situation Awareness: Monitoring 2 Versus 3 Collocated Display Monitors.

PURPOSE: This study aimed to assess the effect of monitoring 2 versus 3 collocated displays on radiation therapist technologists' (RTTs) workload (WL) and situation awareness (SA) during routine treatment delivery tasks. METHODS AND MATERIALS: Seven RTTs completed 4 simulated treatment delivery scenarios (2 scenarios per experimental condition; 2 vs 3 collocated displays) in a within-subject experiment. WL was subjectively measured using the National Aeronautics and Space Administration (NASA) Task Load Index, and objectively measured using eye activity measures. SA was subjectively measured using the SA rating technique, and objectively measured using the SA global assessment technique. Two-tailed paired t tests were conducted to test for differences in means when parametric assumptions were satisfied, otherwise Wilcoxon signed-rank tests were conducted. A .05 level of significance was applied to all statistical tests. RESULTS: No statistically and clinically significant differences were observed between monitoring 2 versus 3 monitors on eye tracking measures (blink rate: 9.4 [4.8] vs 9.6 [4.0]; task evoked pupillary response: 0.16 [0.14] vs 0.21 [0.15]; NASA Task Load Index: 34.7 [19.8] vs 35.3 [20.4]; SA rating technique: 19.3 [6.2] vs 19.5 [7.0]; and SA global assessment technique scores: 100 [0] vs 100 [0]). CONCLUSIONS: Our preliminary findings suggest that monitoring 3 collocated displays by 1 RTT does not impact WL and SA compared with monitoring 2 collocated displays. Only 2 of many possible configurations were investigated. If institutions removed the 3rd display based on the results of this study, there could be unforeseen error(s) if that display helped in situations not assessed in this study.

Impact of Workspace Design on Radiation Therapist Technicians' Physical Stressors, Mental Workload, Situation Awareness, and Performance.

PURPOSE: Our purpose was to assess the effect of workspace configuration on radiation therapists' (RTs) physical stressors, mental workload (WL), situational awareness (SA), and performance during routine treatment delivery tasks in a simulated environment. METHODS AND MATERIALS: Fourteen RTs were randomized to 2 workspace configurations while performing 4 simulated scenarios: current (not ergonomically optimized; n = 7) and enhanced (ergonomically optimized, n = 7). Physical stressors were objectively assessed using a rapid upper limb assessment tool. Mental WL was measured at the end of each simulated scenario subjectively using the NASA Task-Load Index and objectively throughout the scenario using eye-tracking metrics (pupil diameter and blink rate). SA was measured at the end of each simulated scenario subjectively using the situation awareness and review technique. Performance was measured objectively via assessment of time-out compliance, error detection, and procedural compliance. Analysis of variance was used to test the effect of workspace configuration on physical stressors, mental WL, SA, and performance. RESULTS: The enhanced configuration significantly reduced physical stressors (rapid upper limb assessment; P < .01) and resulted in a higher rate of time-out compliance (P = .01) compared with current workspace configuration. No significant effect on other metrics was measured. CONCLUSIONS: Our results suggest that an ergonomically designed workspace may minimize physical stressors and improve the performance of RTs.

Relationship Between Acute Physical Fatigue and Cognitive Function During Orthostatic Challenge in Men and Women: A Neuroergonomics Investigation.

BACKGROUND: Postflight orthostatic challenge (OC), resulting from blood pooling in lower extremities, is a major health concern among astronauts that fly long-duration missions. Additionally, astronauts undergo physical demanding tasks resulting in acute fatigue, which can affect performance. However, the effects of concurrent OC and acute physical fatigue on performance have not been adequately investigated. OBJECTIVE: The purpose of this study was to determine the relationship between acute physical fatigue and cognitive function during OC. METHODS: Sixteen healthy participants performed the mental arithmetic task and psychomotor tracking tasks in the absence and presence of a prior 1-hour physically fatiguing exercise, on separate days under OC (induced via lower body negative pressure). We recorded task performances on the cognitive tests and prefrontal cortex oxygenation using functional near-infrared spectroscopy, along with physiological and subjective responses. RESULTS: The introduction of the cognitive tasks during OC increased cerebral oxygenation; however, oxygenation decreased significantly with the cognitive tasks under the acute fatigue conditions, particularly during the tracking task and in males. These differences were accompanied by comparable task performances. DISCUSSION: The findings suggest that mental arithmetic is a more effective countermeasure than psychomotor tracking under acute physical fatigue during OC. Whereas females did not show a significant difference in cerebral oxygenation due to task, males did, suggesting that it may be important to consider gender differences when developing countermeasures against OC.

Effect of Simulation-Based Training and Neurofeedback Interventions on Radiation Technologists' Workload, Situation Awareness, and Performance.

PURPOSE: Our purpose was to assess the effect of a combined intervention - simulation-based training supported by neurofeedback sessions - on radiation technologists' (RTs') workload, situation awareness, and performance during routine quality assurance and treatment delivery tasks. METHODS AND MATERIALS: As part of a prospective institutional review board approved study, 32 RTs previously randomized to receive versus not receive simulation-based training focused on patient safety were again randomized to receive versus not receive a 3-week neurofeedback intervention (8 sessions of alpha-theta protocol) focused on stress reduction as well as conscious precision, strong focus, and ability to solve arising problems. Perceived workload was quantified using the NASA Task Load Index. Situation awareness was quantified using the situation awareness rating technique. Performance score was calculated using procedural compliance with time-out components and error detection. RESULTS: RTs randomized to simulation-based training followed by neurofeedback sessions demonstrated no significant changes in perceived workload or situation awareness scores, but did have better performance compared with other study groups (P < .01). CONCLUSIONS: This finding is encouraging and provides basis for using neurofeedback as means to possibly augment performance improvements gained during simulation-based training.

Veteran-Centered Investigation of Architectural and Space Design Considerations for Post-Traumatic Stress Disorder (PTSD).

AIM: This study sought to investigate architectural and space design considerations for veterans with post-traumatic stress disorder (PTSD). BACKGROUND: Anecdotal evidence suggests that urban design features could have a positive impact on the mental well-being of individuals suffering from PTSD. However, evidence-based architectural and space design guidelines for PTSD are largely absent. METHODS: Semi-structured interviews were conducted with 17 veterans diagnosed with PTSD to gain insights into their personal experiences with physical indoor and outdoor spaces, and to inquire about their needs and expectations for future architectural design. Transcripts were analyzed thematically. RESULTS: Architectural design features including windows, entrances and exits, walkways and hallways, open space, defensible space, and green space; interior design features including furnishings and color; and ambient features including light, air quality, and noise levels were identified as most influential design features. CONCLUSIONS: Our results underscore the first important step to developing comprehensive architectural and space design guidelines for veterans with PTSD. Work is in progress to solicit more feedback from veterans.

Impact of Simulation-Based Training on Radiation Therapists' Workload, Situation Awareness, and Performance.

PURPOSE: This study aimed to assess the impact of simulation-based training intervention on radiation therapy therapist (RTT) mental workload, situation awareness, and performance during routine quality assurance (QA) and treatment delivery tasks. METHODS AND MATERIALS: As part of a prospective institutional review board-approved study, 32 RTTs completed routine QA and treatment delivery tasks on clinical scenarios in a simulation laboratory. Participants, randomized to receive (n = 16) versus not receive (n = 16) simulation-based training had pre- and postintervention assessments of mental workload, situation awareness, and performance. We used linear regression models to compare the postassessment scores between the study groups while controlling for baseline scores. Mental workload was quantified subjectively using the NASA Task Load Index. Situation awareness was quantified subjectively using the situation awareness rating technique and objectively using the situation awareness global assessment technique. Performance was quantified based on procedural compliance (adherence to preset/standard QA timeout tasks) and error detection (detection and correction of embedded treatment planning errors). RESULTS: Simulation-based training intervention was associated with significant improvements in overall performance (P < .01), but had no significant impact on mental workload or subjective/objective quantifications of situation awareness. CONCLUSIONS: Simulation-based training might be an effective tool to improve RTT performance of QA-related tasks.

Field Methods to Quantify Emergency Responder Fatigue: Lessons Learned from sUAS Deployment at the 2018 Kilauea Volcano Eruption.

OCCUPATIONAL APPLICATIONS There has been increasing use of small unmanned aerial systems in disaster and incident response. We evaluated sUAS pilot states during the tactical response to the 2018 Kilauea Volcano Lower East Rift Zone event, using a 3-minute psychomotor vigilance test (PVT) and wrist worn heart rate sensor. The field data, collected over four days, indicated that the sUAS pilots did not recover to baseline vigilance and physiological levels. Some pilots stopped participating over time, owing to logistical constraints of performing the 3-minute PVT test. Additionally, all pilots refrained from rating their perceived workload levels. We summarize the utility of and challenges associated with collecting performance, physiological, and subjective measures of pilot fatigue during real disaster response.

Electronic health records (EHR) simulation-based training: a scoping review protocol.

INTRODUCTION: Effective electronic health record (EHR)-based training interventions facilitate improved EHR use for healthcare providers. One such training intervention is simulation-based training that emphasises learning actual tasks through experimentation in a risk-free environment without negative patient outcomes. EHR-specific simulation-based training can be employed to improve EHR use, thereby enhancing healthcare providers' skills and behaviours. Despite the potential advantages of this type of training, no study has identified and mapped the available evidence. To fill that gap, this scoping review will synthesise the current state of literature on EHR simulation-based training. METHODS AND ANALYSIS: The Arksey and O'Malley methodological framework will be employed. Three databases (PubMed, Embase and Cumulative Index to Nursing and Allied Health Literature) will be searched for published articles. ProQuest and Google Scholar will be searched to identify unpublished articles. Databases will be searched from inception to 29 January 2020. Only articles written in English, randomised control trials, cohort studies, cross-sectional studies and case-control studies will be considered for inclusion. Two reviewers will independently screen titles and abstracts against inclusion and exclusion criteria. Then, they will review full texts to determine articles for final inclusion. Citation chaining will be conducted to manually screen references of all included studies to identify additional studies not found by the search. A data abstraction form with relevant characteristics will be developed to help address the research question. Descriptive numerical analysis will be used to describe characteristics of included studies. Based on the extracted data, research evidence of EHR simulation-based training will be synthesised. ETHICS AND DISSEMINATION: Since no primary data will be collected, there will be no formal ethical review. Research findings will be disseminated through publications, presentations and meetings with relevant stakeholders.

Evaluating effectiveness of information visualizations using cognitive fit theory: A neuroergonomics approach.

Information visualizations may be evaluated from the perspective of how they match tasks that must be performed with them, a cognitive fit perspective. However, there is a gap between the high-level references made to cognitive fit and the low-level ability to identify and measure it during human interaction with visualizations. We bridge this gap by using an electroencephalography metric derived from frontal midline theta power and parietal alpha power, known as the task load index, to determine if cognitive effort measured at the level of cortical activity is less when cognitive fit is present compared to when cognitive fit is not. We found that when there is cognitive fit between the type of problem to be solved and the information displayed by a system, the task load index is lower compared to when cognitive fit is not present. We support this finding with subjective (NASA task load index) and performance (response time and accuracy) measures. Our approach, using electroencephalography, provides supplemental information to self-report and performance measures. Findings from this study are important because they (1) provide more validity to the cognitive fit theory using a neurophysiological measure, and (2) use the electroencephalography task load index metric as a means to assess cognitive workload and effort in general.

Technologies for Opioid Use Disorder Management: Mobile App Search and Scoping Review.

BACKGROUND: Advances in technology engender the investigation of technological solutions to opioid use disorder (OUD). However, in comparison to chronic disease management, the application of mobile health (mHealth) to OUD has been limited. OBJECTIVE: The overarching aim of our research was to design OUD management technologies that utilize wearable sensors to provide continuous monitoring capabilities. The objectives of this study were to (1) document the currently available opioid-related mHealth apps, (2) review past and existing technology solutions that address OUD, and (3) discuss opportunities for technological withdrawal management solutions. METHODS: We used a two-phase parallel search approach: (1) an app search to determine the availability of opioid-related mHealth apps and (2) a scoping review of relevant literature to identify relevant technologies and mHealth apps used to address OUD. RESULTS: The app search revealed a steady rise in app development, with most apps being clinician-facing. Most of the apps were designed to aid in opioid dose conversion. Despite the availability of these apps, the scoping review found no study that investigated the efficacy of mHealth apps to address OUD. CONCLUSIONS: Our findings highlight a general gap in technological solutions of OUD management and the potential for mHealth apps and wearable sensors to address OUD.

Classifying Major Depressive Disorder Using fNIRS During Motor Rehabilitation.

Major depressive disorder (MDD) has shown to negatively impact physical recovery in a variety of medical events (e.g., stroke and spinal cord injuries). Yet depression assessments, which are typically subjective in nature, are seldom considered to develop or guide rehabilitation strategies. The present study developed a predictive depression assessment technique using functional near-infrared spectroscopy (fNIRS) that can be rapidly integrated or performed concurrently with existing physical rehabilitation tasks. Thirty-one volunteers, including 14 adults clinically diagnosed with MDD and 17 healthy adults, participated in the study. Brain oxy-hemodynamic (HbO) responses were recorded using a 16-channel wearable continuous-wave fNIRS device while the volunteers performed the Grasp and Release Test in four 16-minute blocks. Ten features, extracted from HbO signals, from each channel served as inputs to XGBoost and Random Forest algorithms developed for each block and combination of successive blocks. Top 5 common features resulted in a classification accuracy of 92.6%, sensitivity of 84.8%, and specificity of 91.7% using the XGBoost classifier. This study identified mean HbO, full width half maximum and kurtosis, as specific neuromarkers, for predicting MDD across specific depression-related regions of interests (i.e., dorsolateral and ventrolateral prefrontal cortex). Our results suggest that a wearable fNIRS head probe monitoring specific brain regions, and limiting extraction to few features, can enable quick setup and rapid assessment of depression in patients. The overarching goal is to embed predictive neurotechnology during post-stroke and post-spinal-cord-injury rehabilitation sessions to monitor patients' depression symptomology so as to actively guide decisions about motor therapies.

Neural Efficiency of Human-Robotic Feedback Modalities Under Stress Differs With Gender.

Sensory feedback, which can be presented in different modalities - single and combined, aids task performance in human-robotic interaction (HRI). However, combining feedback modalities does not always lead to optimal performance. Indeed, it is not known how feedback modalities affect operator performance under stress. Furthermore, there is limited information on how feedback affects neural processes differently for males and females and under stress. This is a critical gap in the literature, particularly in the domain of surgical robotics, where surgeons are under challenging socio-technical environments that burden them physiologically. In the present study, we posited operator performance as the summation of task performance and neurophysiological cost of maintaining that performance. In a within-subject design, we used functional near-infrared spectroscopy to assess cerebral activations of 12 participants who underwent a 3D manipulation task within a virtual environment with concurrent feedback (visual and visual + haptic) in the presence and absence of a cognitive stressor. Cognitive stress was induced with the serial-7 subtraction test. We found that while task performance was higher with visual than visual + haptic feedback, it degraded under stress. The two feedback modalities were found to be associated with varying neural activities and neural efficiencies, and these were stress- and gender-dependent. Our findings engender further investigation into effectiveness of feedback modalities on males and females under stressful conditions in HRI.

Correction to: The past, present and future of opioid withdrawal assessment: a scoping review of scales and technologies.

Following publication of the original article [1], the authors reported an error in one of the authors' names. In this Correction the incorrect and correct author name are shown. The original publication of this article has been corrected.

The past, present and future of opioid withdrawal assessment: a scoping review of scales and technologies.

BACKGROUND: A common challenge with all opioid use disorder treatment paths is withdrawal management. When withdrawal symptoms are not effectively monitored and managed, they lead to relapse which often leads to deadly overdose. A prerequisite for effective opioid withdrawal management is early identification and assessment of withdrawal symptoms. OBJECTIVE: The objective of this research was to describe the type and content of opioid withdrawal monitoring methods, including surveys, scales and technology, to identify gaps in research and practice that could inform the design and development of novel withdrawal management technologies. METHODS: A scoping review of literature was conducted. PubMed, EMBASE and Google Scholar were searched using a combination of search terms. RESULTS: Withdrawal scales are the main method of assessing and quantifying opioid withdrawal intensity. The search yielded 18 different opioid withdrawal scales used within the last 80 years. While traditional opioid withdrawal scales for patient monitoring are commonly used, most scales rely heavily on patients' self-report and frequent observations, and generally suffer from lack of consensus on the criteria used for evaluation, mode of administration, type of reporting (e.g., scales used), frequency of administration, and assessment window. CONCLUSIONS: It is timely to investigate how opioid withdrawal scales can be complemented or replaced with reliable monitoring technologies. Use of noninvasive wearable sensors to continuously monitor physiologic changes associated with opioid withdrawal represents a potential to extend monitoring outside clinical setting.